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Russian Scientists Invent Cost-Effective Method to Neutralize Mold Toxins in Grain

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Russian scientists have developed a safe and affordable method to extract and neutralize mold toxins in grain, specifically targeting the harmful mycotoxin zearalenone.


Russian Scientists Develop Innovative Method to Combat Mold Toxins in Grain

Researchers at Saratov State University have unveiled a groundbreaking method for extracting and neutralizing harmful mold toxins in grain, specifically targeting the mycotoxin zearalenone. This toxin, produced by mold species such as Fusarium and Gibberella, poses significant health risks to both animals and humans, particularly affecting reproductive systems. The study, supported by the Russian Science Foundation, emphasizes the importance of safe and cost-effective solutions in agricultural practices.

The Science Behind the Breakthrough

The innovative approach involves the creation of a special protein reagent that binds to zearalenone, simplifying the process of identifying and neutralizing this dangerous compound. Traditional methods of testing grain for mold toxins often involve molecular imprinting, which can be hazardous and expensive. However, the new method utilizes a synthesized analogue of the toxin, allowing for safer laboratory conditions and reduced costs.

Chemists successfully labeled serum albumin molecules with the new compound, which were then attached to silicon oxide nanoparticles. These nanoparticles, with their porous surfaces, enable multiple protein molecules to bind effectively to zearalenone. Laboratory tests indicated that the new receptor can bind 73% of zearalenone molecules, demonstrating a comparable efficacy to conventional methods, which bind 82%.

Implications for Agriculture and Food Safety

The implications of this research are significant for the agricultural sector. The newly developed bioimprinting method not only reduces the cost of testing systems for mycotoxins but also enhances their accessibility. Professor Natalia Burmistrova highlighted the potential for reusing up to 70% of the original toxin substitute reagent, which could improve the commercial viability of this innovative material. The safe application of this method could lead to a decrease in mycotoxin poisoning in livestock, ultimately benefiting food safety and public health.

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