Research Unveils Life-Prolonging Nutritional Compound to Combat Alzheimer's
Recent studies by scientists from the University of Seville in Spain and the University of Kent in the UK have highlighted the potential of carotenoid phytoene in extending lifespan and combating Alzheimer's disease. Published in the journal Antioxidants, the research showcases phytoene's ability to enhance the lifespan of roundworms, a model organism for studying Alzheimer's, by 10 to 18.6%. This compound also demonstrated a significant reduction in the toxic effects of amyloid plaques, which are closely associated with the onset of Alzheimer's symptoms.
Carotenoids, including phytoene, are essential nutrients found in various fruits and vegetables like tomatoes, carrots, and red peppers. While most carotenoids are known for their vibrant colors, phytoene is unique as it is colorless and has previously been overlooked for its biological activity in humans. This research opens up new avenues for understanding how such compounds can mitigate cognitive decline and enhance overall health, particularly in aging populations.
The study's lead researcher, Dr. Paula Mapelli-Bram, expressed optimism about the findings, stating, "These are very exciting preliminary results, and we are seeking funding to continue this line of research and find out the mechanisms through which these effects are produced." The research team tested both pure phytoene and extracts from microalgae, emphasizing the need for further exploration into the health benefits of carotenoids and their potential applications in dietary supplements and nutraceuticals.